Rare

Autoinflammatory

Conditions

Community – UK

Tsuchida, N., Kirino, Y., Soejima, Y. et al. Haploinsufficiency of A20 caused by a novel nonsense variant or entire deletion of TNFAIP3 is clinically distinct from Behçet’s disease. Arthritis Res Ther 21, 137 (2019). https://doi.org/10.1186/s13075-019-1928-5

Aeschlimann FA, Batu ED, Canna SW, Go E, Gül A, Hoffmann P, Leavis HL, Ozen S, Schwartz DM, Stone DL, van Royen-Kerkof A, Kastner DL, Aksentijevich I, Laxer RM. A20 haploinsufficiency (HA20): clinical phenotypes and disease course of patients with a newly recognised NF-kB-mediated autoinflammatory disease. Ann Rheum Dis. 2018 May;77(5):728-735. doi: 10.1136/annrheumdis-2017-212403. Epub 2018 Jan 9. PMID: 29317407.

Yu, MP., Xu, XS., Zhou, Q. et al. Haploinsufficiency of A20 (HA20): updates on the genetics, phenotype, pathogenesis and treatment. World J Pediatr 16, 575–584 (2020). https://doi.org/10.1007/s12519-019-00288-6